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Carboxylic acids and derivatives

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Carboxylic acid introductionCarboxylic acid naming
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Fischer esterificationAcid chloride formationAmides, anhydrides, esters, and acyl chloridesRelative stability of amides, esters, anhydrides, and acyl chloridesAmide formation from acyl chloride
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Carboxylic acid nomenclature and propertiesReduction of carboxylic acidsPreparation of acyl (acid) chloridesPreparation of acid anhydridesPreparation of esters via Fischer esterificationPreparation of amides using DCCDecarboxylation
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Nomenclature and properties of acyl (acid) halides and acid anhydridesNomenclature and properties of estersNomenclature and properties of amidesReactivity of carboxylic acid derivativesNucleophilic acyl substitutionAcid-catalyzed ester hydrolysisAcid and base-catalyzed hydrolysis of amidesBeta-lactam antibiotics

About this unit

Did you know that many fruit aromas including banana (isoamyl acetate) and pineapple (ethyl butanoate) come from molecules containing ester groups? These compounds can be synthesized from carboxylic acids using a reaction called Fischer esterification. We will be covering naming carboxylic acids, as well as the diverse chemistry of carboxylic acid derivatives such as acid chlorides, amides, esters, and anhydrides.