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Fertilization and implantation

Formation of zygote, development of blastocyst, and implantation.
This article offers a quick refresher on the events and structures involved in human fertilization and implantation.

Key terms

TermMeaning
fertilizationfusion of male and female gametes (sperm and egg)
zygotediploid cell formed by fusion of gametes
cleavagemitotic division of zygote
blastomeredaughter cell produced by cleavage
blastocyststructure that develops from morula; has inner cell mass and outer trophoblast
implantationembedding of blastocyst in endometrial lining

What happens during fertilization?

In humans, fertilization occurs when a single sperm and egg cell fuse to form a zygote.
The zygote then divides rapidly as it travels to the uterus, where it attaches to the endometrial lining, and leads to pregnancy.
Let's take a brief look at the zygote's journey.

Cleavage and implantation

The image below summarizes the events that occur between fertilization (A) and implantation (H).
The table below lists the key features of the labelled events in the image.
ABC-FGH
FertilizationZygote formationCleavageBlastocyst formationImplantation
Single sperm fuses with ootidSingle, diploid cell2-8 blastomeres, morula (F) with 16 blastomeresTrophoblast and inner cell mass differentiatedUterine cells dividing to cover blastocyst
test your understanding
Identify the blastocyst from the structures below.
Choose 1 answer:

test your understanding
The events of fertilization and implantation are depicted below, numbered in order of occurrence.
At which stage has mitotic division of the zygote begun?
Choose 1 answer:

test your understanding
Which of the following structures transforms into the blastocyst?
Choose 1 answer:

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