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Course: MCAT > Unit 2
Lesson 3: Foundation 3: Organ Systems- What is this passage set and how is it organized?
- How to use this passage set
- Nervous/immune systems: Effects of vagotomy on immune response
- Nervous/immune systems: Demyelinating disease
- Nervous system: Effects of stroke on the brain
- Nervous system: Opioid receptors and naloxone
- Nervous system: Organization of motor neurons
- Neuromuscular junction: Acetylcholinesterase inhibitors
- Neuromuscular junction: Repetitive nerve stimulation in myasthenia gravis
- Muscles: Duchenne muscular dystrophy
- Skeletal system: Bone development
- Skeletal system: Disorders of bone remodeling
- Endocrine: Cushing syndrome and the HPA axis
- Endocrine: Measuring hormone levels
- Metabolism: Medical case: Fussy child
- Metabolism: The role of brown fat
- Medical case: Type 1 diabetes
- Metabolism: The discovery of leptin
- Metabolism: Do artificial sweeteners increase diabetes risk?
- GI system: Pancreatitis studies
- GI system: H. pylori infection and stomach cancer
- GI system: Role of alcohol in pancreatitis
- GI system: Lymphatic function during cirrhosis
- Respiratory system: Lung volume studies
- Cardiovascular system: Detection of myocardial infarction
- Cardiovascular system: Anemia and clinical case
- Cardiovascular system: Oxygen affinity of hemoglobin and myoglobin
- Immune system: Milk allergy and intolerance
- Immune system: Mechanisms of antibody variability
- Immune system: T cell activation
- Immune system: Acute vs chronic inflammation
- Immune system: Antibody class differences
- Renal: Measuring GFR with inulin
- Renal: RAAS inhibitors, mechanisms and effects
- Renal: Congestive heart failure and diuretics
- Skin: Laser tattoo removal
- Skin/immune system: Lasers as vaccine adjuvants
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What is this passage set and how is it organized?
This article introduces this passage set, which covers topics from Foundation 3 of the MCAT. It also discusses how the Foundation 3 passages are organized by topic, roughly in line with the AAMC blueprint.
The passages you’ll find in this set cover biology topics from AAMC Foundation 3. This foundation, along with Foundations 1 and 2 (tested in the other passage sets in this unit), is part of the Biological and Biochemical Foundations of Living Systems section of the MCAT. Foundation 3 covers topics in organ system anatomy and physiology, whereas Foundation 1 covers biochemical processes that occur within the cell and the principles that govern them, and Foundation 2 covers cell biology topics.
This statement by the AAMC describes the significance of Foundation 3 topics for pre-medical students: “As a result of the integration of a number of highly specialized organ systems, complex living things are able to maintain homeostasis while adapting to a constantly changing environment and participating in growth and reproduction.”
Many of the MCAT passages in this section test your knowledge of organ systems, as well as your ability to interpret new, passage-based information. Passage information may involve (normal) physiology and (abnormal) pathophysiology, or disease states, or in vitro and in vivo anatomy and physiology studies.
Passages in this set are labeled with topics that roughly align with those listed in the AAMC Biological and Biochemical Foundations blueprint, under Foundation 3. The passages are also organized by topic, in an order consistent with the AAMC blueprint. The topic of each passage is indicated by its subtitle, as circled below.
Here is a list of our Foundation 3 passage topics and their corresponding AAMC content categories:
Content Category 3A: Structure and functions of the nervous and endocrine systems and ways these systems coordinate the organ systems
- Nervous system
- Neuromuscular junction
- Endocrine
Content Category 3B: Structure and integrative functions of the main organ systems
- Muscles
- Skeletal system
- Metabolism
- GI system
- Respiratory system
- Cardiovascular system
- Immune system
- Renal
- Skin
- Reproductive system