Eukaryotic gene transcription: Going from DNA to mRNA
An analogy for understanding transcription
The mechanics of transcription
What does an mRNA transcript look like?
- First, add a hydroxyl group to the 2’ carbon of each deoxyribose. In biochemist speak, you need to hydroxylate the 2’ deoxyriboses.
- Second, snip the methyl group off of every thymine that occurs in the nucleotide strand. In biochemist speak, you need to demethylate each thymine.
|bonds between nucleotides||phosphodiester||phosphodiester|
|sugar in nucleotides||deoxyribose||ribose|
|nucleobases||adenine, thymine, guanine, cytosine||adenine, uracil, guanine, cytosine|
|primary function||information storage|