https://www.khanacademy.org/science/ap-biology/heredity/non-mendelian-genetics/e/non-mendelian-genetics-exercise 2026-03-27T03:10:09.572549356Z Non-Mendelian genetics Test your knowledge of non-Mendelian genetics! Megan Cohn exercise https://www.khanacademy.org/science/ap-biology/heredity/non-mendelian-genetics/a/sex-linkage-sex-determination-and-x-inactivation 2024-06-28T21:00:15.59562973Z X-linked inheritance Learn about the chromosomal basis of sex determination, X and Y chromosomes, and X-linkage. article https://www.khanacademy.org/science/grade-11-biology-snc-aligned/x58c107ba92d3f0b2:domain-h-reproduction-and-inheritance/x58c107ba92d3f0b2:sex-determination-and-sex-linked-inheritance/v/sex-linked-traits 2022-11-16T04:22:43.7414897Z Sex-linked traits Sex-linked traits are characteristics that are determined by genes located on the sex chromosomes. Inheritance patterns for these traits can differ for males and females, since the X and Y chromosomes differ. One example of a sex-linked trait is color blindness, which is primarily seen in males. X-inactivation can also influence the expression of sex-linked traits. Sal Khan video https://cdn.kastatic.org/googleusercontent/FKBvCcH73kIpRh8t_XnJzaksoaU7sIFBD5EyR_XHVgE415I5fTibMfnyEw4KKur3KQuU6z-I8hh-SjcOMtpdW_I Sex-linked traits Sex-linked traits are characteristics that are determined by genes located on the sex chromosomes. Inheritance patterns for these traits can differ for males and females, since the X and Y chromosomes differ. One example of a sex-linked trait is color blindness, which is primarily seen in males. X-inactivation can also influence the expression of sex-linked traits. https://cdn.kastatic.org/ka-youtube-converted/-ROhfKyxgCo.mp4/-ROhfKyxgCo.mp4 859 Sex determination and sex-linked inheritance https://www.khanacademy.org/science/ap-biology/heredity/non-mendelian-genetics/v/thomas-hunt-morgan-and-fruit-flies 2024-06-28T21:00:15.59562973Z Thomas Hunt Morgan and fruit flies The groundbreaking work of Thomas Hunt Morgan in the early 1900s provided substantial evidence for the chromosome theory of inheritance. Using fruit flies as a model organism, Morgan discovered a mutant white-eyed male fly and traced its inheritance pattern, revealing a connection between the X sex chromosome and the gene for eye color. This pioneering research earned Morgan a Nobel Prize and cemented the role of chromosomes in genetic inheritance. Sal Khan video https://cdn.kastatic.org/googleusercontent/AjTJJt2sBui612GqPH5WCcYakXgg3VPpaqRlBo4JwFnJbOTnLk_kn5955RIO8rFNPfS7lRaRkyCmZ5x2IcquPQ2zcg Thomas Hunt Morgan and fruit flies The groundbreaking work of Thomas Hunt Morgan in the early 1900s provided substantial evidence for the chromosome theory of inheritance. Using fruit flies as a model organism, Morgan discovered a mutant white-eyed male fly and traced its inheritance pattern, revealing a connection between the X sex chromosome and the gene for eye color. This pioneering research earned Morgan a Nobel Prize and cemented the role of chromosomes in genetic inheritance. https://cdn.kastatic.org/ka-youtube-converted/huDDaj0PjLU.mp4/huDDaj0PjLU.mp4 640 Sex determination and sex-linked inheritance https://www.khanacademy.org/science/ap-biology/heredity/chromosomal-inheritance-ap/a/discovery-of-the-chromosomal-basis-of-inheritance 2023-08-07T17:09:37.131449861Z The chromosomal basis of inheritance Thomas Hunt Morgan's experiments. The fruit fly (Drosophila melanogaster) as a model system. article https://www.khanacademy.org/science/ap-biology/heredity/non-mendelian-genetics/v/pedigree-for-determining-probability-of-exhibiting-sex-linked-recessive-trait 2024-06-28T21:00:15.59562973Z Pedigree for determining probability of exhibiting sex linked recessive trait Pedigree charts can be used to determine the probability of offspring exhibiting an X-linked recessive trait, such as color blindness. By scrutinizing genotypes and utilizing a Punnett square, the probability of color blindness in offspring can be calculated. Sal Khan video https://cdn.kastatic.org/googleusercontent/ztSXY74ehvHg_rqgl3MStecKwOBRsQw-aX1osy0smpv3fYD38hwM7CIYzI5XZ4_U0SA992TAAdbhT8w-fEuwxUMk Pedigree for determining probability of exhibiting sex linked recessive trait Pedigree charts can be used to determine the probability of offspring exhibiting an X-linked recessive trait, such as color blindness. By scrutinizing genotypes and utilizing a Punnett square, the probability of color blindness in offspring can be calculated. https://cdn.kastatic.org/ka-youtube-converted/DzP7XO0Qg_Y.mp4/DzP7XO0Qg_Y.mp4 319 Sex determination and sex-linked inheritance https://www.khanacademy.org/science/hs-bio/x230b3ff252126bb6:inheritance-and-variation-of-traits/x230b3ff252126bb6:complex-patterns-of-inheritance/e/apply-complex-patterns-of-inheritance 2025-04-03T16:34:47.284665315Z Apply: complex patterns of inheritance Apply your understanding of complex patterns of inheritance in this set of free, standards-aligned practice questions. Megan Cohn exercise https://www.khanacademy.org/science/hs-bio/x230b3ff252126bb6:inheritance-and-variation-of-traits/x230b3ff252126bb6:complex-patterns-of-inheritance/v/example-punnet-square-for-sex-linked-recessive-trait 2024-06-28T21:00:15.59562973Z Worked example: Punnett square for sex-linked recessive trait Hemophilia, an X-linked recessive trait, affects blood clotting. A carrier woman and a hemophiliac man have a 50% chance of having a daughter with hemophilia. This is determined through a Punnett square, which shows the possible combinations of the parents' alleles. The Punnett square can also answer other questions, like the chance of having a hemophiliac son or a non-hemophiliac offspring. Sal Khan video https://cdn.kastatic.org/googleusercontent/YZFIfs43p4XNJl-B0HluzfTKeXoMeP7W7q1b50VX4hZvhoN4p4bLgHxf5Ny2hISa7nHjV1UQj2OIkpqVbHhrw9dO Worked example: Punnett square for sex-linked recessive trait Hemophilia, an X-linked recessive trait, affects blood clotting. A carrier woman and a hemophiliac man have a 50% chance of having a daughter with hemophilia. This is determined through a Punnett square, which shows the possible combinations of the parents' alleles. The Punnett square can also answer other questions, like the chance of having a hemophiliac son or a non-hemophiliac offspring. https://cdn.kastatic.org/ka-youtube-converted/I_DjmWS_9cg.mp4/I_DjmWS_9cg.mp4 294 Sex determination and sex-linked inheritance