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Renal regulation of blood pressure

9 videos
3B: In addition to fluid and electrolyte balance, the kidneys play an essential role in regulating blood pressure. When the nephron, the functional unit of the kidney, senses that it is not receiving much blood flow, it knows something is up. So begins a cascade which allows the nephron to reabsorb more fluid from the urine, in attempt to fill up the perceived dip in blood volume. Here you will learn the mechanism of ADH and the renin-angiotensin-aldosterone system in sustaining this homeostasis.

General overview of the RAAS system: Cells and hormones

VIDEO 14:09 minutes
Learn the important cells and hormones that are working together to control your blood pressure! Rishi is a pediatric infectious disease physician and works at Khan Academy.

Renin production in the kidneys

VIDEO 14:09 minutes
Learn the three major triggers for Renin production by the Juxtaglomerular cells. Rishi is a pediatric infectious disease physician and works at Khan Academy.

Activating angiotensin 2

VIDEO 10:20 minutes
See how Renin and ACE work to cut Angiotensinogen down to size! Rishi is a pediatric infectious disease physician and works at Khan Academy.

Angiotensin 2 raises blood pressure

VIDEO 10:40 minutes
See how Angiotensin 2 effects 4 target "organs" to increase blood pressure. Rishi is a pediatric infectious disease physician and works at Khan Academy.

Aldosterone raises blood pressure and lowers potassium

VIDEO 13:18 minutes
See how Aldosterone effects the principal cells of the kidney to raise BP and lower potassium. Rishi is a pediatric infectious disease physician and works at Khan Academy.

Aldosterone removes acid from the blood

VIDEO 11:20 minutes
See how Aldosterone acts on the alpha-intercalated cell to remove protons (acid) from the blood. Rishi is a pediatric infectious disease physician and works at Khan Academy.

ADH secretion

VIDEO 15:05 minutes
Learn the key triggers for ADH secretion. Rishi is a pediatric infectious disease physician and works at Khan Academy.

ADH effects on blood pressure

VIDEO 9:33 minutes
See how ADH acts on blood vessels and the kidney to raise blood pressure. Rishi is a pediatric infectious disease physician and works at Khan Academy.

Aldosterone and ADH

VIDEO 9:47 minutes
Find out how Aldosterone and ADH cause changes in volume and osmolarity. Rishi is a pediatric infectious disease physician and works at Khan Academy.