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Carboxylic acid derivatives

8 videos
5D: As the name would suggest, carboxylic acid derivatives are quite similar to carboxylic acids in their structure and function. If you’ve ever used soap to wash your hand, you have experienced firsthand (pun intended!) the lavatory effects of an ester, one of the many classes of carboxylic acid derivatives. In this tutorial, we will discuss the important nomenclature, properties, and reactions of carboxylic acids.

Nomenclature and properties of acyl (acid) halides and acid anhydrides

VIDEO 10:20 minutes
How to name acyl (acid) chlorides and acid anhydrides and how to analyze their physical properties

Nomenclature and properties of esters

VIDEO 10:31 minutes
How to name esters and how to analyze their physical properties

Nomenclature and properties of amides

VIDEO 8:50 minutes
How to name amides and the physical properties of acetamide

Reactivity of carboxylic acid derivatives

VIDEO 9:03 minutes
How to analyze the reactivity of the carboxylic acid derivatives using induction and resonance effects

Nucleophilic acyl substitution

VIDEO 9:29 minutes
The general mechanism of nucleophilic acyl substitution (and leaving group stability)

Acid-catalyzed ester hydrolysis

VIDEO 11:26 minutes
The mechanism for the acid-catalyzed hydrolysis of esters (and transesterification)

Acid and base-catalyzed hydrolysis of amides

VIDEO 11:47 minutes
The mechanisms for acid and base catalyzed hydrolysis of amides

Beta-lactam antibiotics

VIDEO 9:14 minutes
The mechanism of action of beta-lactam antibiotics